Pierce Brosnan's daughter dies of ovarian cancer age 41
Pierce Brosnan has paid tribute to his daughter Charlotte, who has died of ovarian cancer, aged 41.
In a statement Brosnan said his "darling daughter Charlotte Emily passed on to eternal life" on June 28.
7000 women are diagnosed each year in the UK, with 12 women dying every day from the disease.
Most women diagnosed with ovarian cancer are over the age of 50, but it can occur at any age.
UK survival rates are amongst the lowest in Europe at 36%.
The key symptoms of ovarian cancer include: Increased abdominal size/persistent bloating, pelvic or abdominal pain, difficulty eating or feeling full quickly, needing to pass water more urgently or frequently than usual.
For the average woman there is a 2% or 1 in 50 chance that she will develop ovarian cancer at some point during her lifetime.
If a woman has a mutation in either the BRCA1 or BRCA2 gene, her risk of developing ovarian cancer at some point during her life increases to between 15 and 45%.
Source: Target Ovarian Cancer
It is the same cancer that killed her mother, Cassandra Harris, who was Brosnan's first wife.
"Our hearts are heavy with the loss of our beautiful dear girl," he said. "Charlotte fought her cancer with grace and humanity, courage and dignity."
Brosnan adopted Charlotte and her brother Christopher after their father died in 1986.
Cassandra Harris died in 1990 at age 43. Charlotte had been suffering from the disease for three years.'Pray for a cure'
The statement said that Charlotte had died surrounded by her husband Alex, children Isabella and Lucas and brothers Christopher and Sean.
Brosnan also thanked people for "their heartfelt condolences".
"We pray for her and that the cure for this wretched disease will be close at hand soon," he said.
Annwen Jones, chief executive, of Target Ovarian Cancer has also paid tribute.
"Our deepest condolences go out to the family of Charlotte Brosnan, particularly following the deaths of other family members to the same disease," she said.
"Too few women understand the connection between familial breast and ovarian cancer, and more must be done to raise awareness of the familial links of ovarian cancer, and improve treatments.
"We encourage all women to know their family history - on both their mother's and father's sides, and visit their doctor with any concerns."