5 February 2013
Last updated at 08:11
The first Red Nose Day took place on 5 February 1988, and, ahead of this year's event on 15 March, we look back at some of the highlights of Comic Relief's fund-raising events in Africa and the UK.
The first live television show was watched by more than 30 million people and included comedians of the moment with Griff Rhys Jones, Lenny Henry and Jonathan Ross. It raised £15m.
Comedian Billy Connolly visited projects run by Oxfam and Save the Children in Mozambique in 1989. He returned in 1995 to film documentary The Return to Nose and Beak, in which he worked with Oxfam to reunite children with their parents.
By 1991 the event was biennial, and the first nose with added extras was launched. Called Harry Hands, it is seen here worn by Hale and Pace, who also released The Stonk, selling £200,000 worth of singles.
In 1993, Anthony Mingehella made Together We Can Break Down This Wall, which showed people with a variety of disabilities speaking out against inequality.
In 1995, Dawn French raised £1m by kissing Hugh Grant while wearing a tribute to Liz Hurley’s Versace dress. That year the show raised more than £22m.
That was also the year of the heat-sensitive nose, with a campaign that was all about what a difference a day makes. Here Victoria Wood is in Zimbabwe with people working on an irrigation programme, learning how to make clay pipes to carry water into the fields.
The birth of the furry nose, in 1997, brought in the might of the Spice Girls, accompanied by Dawn French, Jennifer Saunders and Kathy Burke, selling 672,577 copies of the Comic Relief single Who Do You Think You Are?
Lenny Henry also fronted a documentary about young homeless people in London.
That same year Dawn French starred in a special of her sitcom, The Vicar Of Dibley, and hosted a party for Johnny Depp and others.
Richard Curtis (left), who helped to set up Comic Relief back in 1984, is seen here directing Rowan Atkinson in a Doctor Who special, Curse of the Fatal Death.
Two years later Sacha Baron Cohen helped say Pants to Poverty by interviewing David and Victoria Beckham as Ali G. The show had a peak audience of 12.6 million viewers during the night, and the campaign raised more than £55m.
In 2001, Lenny Henry went on tour around the UK, visiting projects and fund-raising events such as this one at Edinburgh Castle. Comic Relief has approved more than £22m of grants in Scotland, with funding going to more than 1,000 projects.
In 2003, Gordon Ramsay travelled to Tanzania in order to help cook at a project for 100 street children.
Ruby Wax and Jo Brand took part in Fame Academy. The winner, voted by viewers, was Will Mellor, but on the night the audience was treated to a one-off special performance of the Cheeky Song.
In 2005, the stars of Little Britain, David Walliams and Matt Lucas, entertained with Elton John.
In 2007, Billy Connolly was once again in Africa, this time visiting Kibera, on the outskirts of Nairobi, and the continent's largest slum.
Also that year, Ricky Gervais's parody appeal film starred Bono, Bob Geldof, Stephen Merchant, Jamie Oliver and Andi Peters.
Noel Edmonds winced on the set of Deal or No Deal as he was joined by Catherine Tate's character Nan.
Gary Barlow and other celebrities from the world of music and television took part in the Big Red Nose Climb in 2009. They conquered Mount Kilimanjaro, raising awareness of the devastating issue of Malaria in Africa, and £3.4m.
The Big Red Nose Desert Trek of 2011 saw nine celebrities trekking 60 miles (100km) across the Kaisut Desert, northern Kenya, highlighting the issues of sight and visiting projects that help to prevent blindness and treat eye conditions. Since funding this issue, Comic Relief has helped to prevent or cure blindness for more than 2.4 million people in some of the world's poorest countries.
Back in the UK, James Cordon was joined by George Michael for the show on BBC1.
Money raised through Red Nose Day has helped to fund Kuapa Kokoo in Ghana, an organisation that ensures farmers get a fair price for their cocoa.
Francis came to the attention of a Red Nose Day funded mental-health project, BasicNeeds, two years ago, when they found him restrained in a bare room. The project helped him receive appropriate treatment, rebuild his family life and return to his job as a teacher.
Earlier this year, David Walliams was in Kenya to meet Philip, who he says was the inspiration behind his 2011 Thames swim. Walliams first met Philip living by the side of the road in Kenya, orphaned and homeless, begging for food. Philip is one of more than one million who have benefitted from Red Nose Day projects, which helped him to get the education he so desperately wants.