Great Manchester Run: Muamba starts race for 40,000
Forty thousand runners are taking part in the Great Manchester Run Manchester, which has been started by former Bolton Wanderers midfielder Fabrice Muamba.
The 10km run - the 11th annual race in the city - is a legacy of the 2002 Commonwealth Games.
Last year, Ethiopian athlete Haile Gebrselassie won the men's race for a fifth time, while the women's race was won by Kenyan Linet Masai.
Muamba suffered a cardiac arrest in an FA cup tie in March 2012.
He recovered even though his heart stopped for 78 minutes and had to be restarted several times.
The former England under-21 player, who retired from football in August on the advice of his doctors, will have 25 runners taking part - one for each year of his life.
He now works with Hearts & Goals, a year-long campaign that aims to prevent death from sudden cardiac arrests.
The campaign has teamed up with charity Arrhythmia Alliance which helps place defibrillators (AEDs) in communities.
It is hoped 92 fans - one from each football league club in England - will take part on behalf of Muamba and the charity.
BBC Radio Manchester presenter Becky Want is leading a BBC team raising money for The Christie Hospital, the station's chosen charity.