Does Middle-East peace process matter?
Does the peace process between Israel and the Palestinians matter to anyone but themselves?
Is this, as the Quartet representative to the Middle East, Tony Blair, and British government spokesmen would have it, the central problem in the Middle East which, if solved, will help to change the broader climate in the region?
Or, given the turmoil in Egypt, Syria, Iraq and beyond, has Israeli-Palestinian peace become an issue apart; less a barometer for regional tensions and more an intractable struggle that shows no sign of ending?
With US-brokered talks between the two sides due to begin again this week there is an all-encompassing sense of diplomatic deja-vu.
We have been here many times before.
There are the almost ritual concessions to get talks going - the release of Palestinian prisoners by Israel; a cloudy understanding either to freeze or restrict new construction in Israeli settlements; and the equally public announcement of new building anyway as a conservative Israeli government seeks to placate domestic opponents of the peace talks to its right.
Given Israel's stark political divisions and the Palestinian split between Hamas in the Gaza Strip and the Fatah-dominated West Bank - not to mention more extreme Islamist groupings antithetical to both - US Secretary of State John Kerry's investment in re-booting the peace process might seem to the casual observer to be naive and destined to end in failure.
But two major trends underpin Mr Kerry's efforts - and for many analysts they make an Israel-Palestinian peace more important now than ever.
One trend is the growing belief in many quarters - you hear it explicitly from British Foreign Secretary William Hague - that the opportunity for a "two-state" solution, a Palestinian state in the West Bank and Gaza Strip living alongside Israel, is fast running out.
"The window for a two-state solution is closing," Mr Hague noted in December last year.
According to this view the occupation risks becoming permanent, raising profound questions about the nature of Israel's democracy and for the way the country is viewed abroad, especially in the West.
The other trend is the chaos and uncertainty ushered in by what used to be called the "Arab Spring".
Popular upheavals have degenerated into military take-over, near anarchy, full-scale civil war and the renewal of bitter sectarian violence.
The crisis in Syria has called into question the very borders of some of the states established in the wake of the departure of the colonial powers after World War II. It is clear that these processes are profound and will unfold over a considerable time period.
It is not so much that an Israel-Palestinian peace will solve any of these problems. It will not. It won't even contribute to resolving them.
But Western diplomats believe that a resolution to one of the world's most intractable disputes could lance a diplomatic boil that inflames passions and tensions way beyond the Middle East and contributes to making a very bad regional situation even worse.