Role of glucagon in control of blood sugar levels – Higher

Negative feedback

In blood glucose regulation, the hormone insulin plays a key role. When blood sugar rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose. Some is stored as body fat and other is stored as glycogen in the liver and muscles. Whereas, if the blood glucose level is too low, the liver receives a message to release some of that stored glucose into the blood. This change is brought about by another hormone produced by the pancreas called glucagon.

This is an example of negative feedback.

A flowchart to demonstrate negative feedback

Action of insulin

Low glucoseHigh glucose
Effect on pancreasInsulin not secreted into the bloodInsulin secreted into the blood
Effect on liverDoes not convert glucose into glycogenConverts glucose into glycogen
Effect on blood glucose levelIncreasesDecreases