Broadcaster Jeremy Vine will step down as presenter of BBC One current affairs show Panorama at the end of the year.
The 45-year-old, who has presented the show since it moved to a Monday evening slot four years ago, said hosting it had been "an incredible experience".
The programme will continue without an anchor, although Vine will still front reports and special episodes.
Vine said the show no longer needed a front person. The BBC, meanwhile, said it would benefit from a "new look".
Panorama editor Tom Giles praised Vine for the "dynamism and enthusiasm" he had brought to the flagship BBC One programme.
He said he could be "be proud of the part he has played" in establishing the show "with a solid and rising audience."
Vine, a former Newsnight regular, will continue to present his lunchtime show on BBC Radio 2.
Last month he was seen introducing Panorama's controversial documentary on alleged Fifa corruption, aired on the eve of the vote on which countries should host the 2018 and 2022 World Cups.