We're bringing this live page to a close now. Before we do, here's a look at some of the key UK headlines today:
- The NHS is setting up vaccination centres across the country in preparation for any Covid jab being approved, Health Secretary Matt Hancock has said
- Vaccination could start as early as next month, with the bulk of vaccination taking place in the new year. The government has now formally asked the Medicines and Healthcare products Regulatory Agency (MHRA) to assess the Pfizer-BioNTech vaccine
- Coronavirus infection rates are levelling off in England and Scotland and decreasing in Wales and Northern Ireland, latest data from the Office for National Statistics suggests
- It comes as more than two million people in Scotland entered the country's toughest level of coronavirus restrictions. Level four rules came into force at 18:00 in 11 council areas across central and western Scotland
- People in Wales have been warned they risk facing strict Christmas measures if Covid-19 infection rates surge. First Minister Mark Drakeford warned people not to "fritter away" the success of the nation's firebreak
- And the government has changed lockdown rules so that Christmas tree farms and sellers can open from Saturday in England
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