Members of the Guernsey branch of the union Unite have voted to strike over what they have described as "a below cost of living pay offer" and claims that a union rep was unfairly dismissed.
It follows talks on Thursday to discuss the latest offer made to public service employees by the government.
They say they are unhappy with the offer on the table for 2019 and are calling for a stoppage of work next Wednesday.
Staff affected include cleaners and porters as well as housekeeping and maintenance workers at the hospital, States Works and the Airport Fire Service.
Unite says essential operations at the hospital and airport will not be affected, but the Policy and Resources Committee is urging them to reconsider and reopen negotiations.
Deputy Gavin St Pier described today's announcement as disappointing and "no way to negotiate".