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Greater Manchester Fire and Rescue Service
Fire stations will close and engine numbers will be cut as part of plans to save Greater Manchester £12.8m over the next three years.
Greater Manchester Fire and Rescue Service said the reforms would add a "negligible" 10 seconds to response times.
Six stations earmarked for closure - Bolton Central, Bolton North, Stockport King Street, Whitehill in Stockport, Philips Park and Manchester Central - will be replaced by three new sites.
The brigade's total number of appliances will be cut from 56 to 47 and 113 support staff roles will be made redundant.
The region's mayor and fire commissioner Andy Burnham said cuts would allow the fire brigade to focus on a "front-line first" approach to saving lives.
Fire Brigades Union representative for Greater Manchester Gary Keary said the fire service had been harmed by budget cuts and the brigade "must fight any further deterioration".