A person was critically injured when a car crashed in Devon and ended up on an embankment close to a railway line.
Two vehicles were involved in the collision on the A377 near Umberleigh, close to King's Nympton railway station, at about 15:00 GMT.
A train had to stop to avoid the vehicle beside the track and the casualty was airlifted to hospital, Devon and Cornwall Police said.
The second vehicle was left badly damaged on the road.
Three further casualties were treated by ambulance crews, the fire service said.
The A377 has been closed between Station Road and the B3226.
Police said the road, which had lots of standing water, was expected to be closed for some time.
Trains between Barnstaple and Exeter St Davids have been disrupted.
After the line was shut for an investigation, trains were later allow to pass the scene at 5mph (8km/h).