Derby-based train maker Bombardier is hiring up to 400 temporary staff on one-year contracts.
The drive comes as the firm enters a busy period with several contracts coming to an end over the next year.
Interviews for the jobs will take place during a recruitment day at Pride Park Stadium on 21 August.
The firm is encouraging workers laid off by other firms in the area, such as JCB and Toyota, to get in touch.
'Sharp drop' anticipated
Staffordshire-based JCB has laid off 2,000 workers, while Toyota has started a voluntary release programme in a bid to trim its workforce by about 850.
Bombardier makes trains for the London Underground and is hoping to win a contract to build Thameslink carriages.
Neil Harvey, communications director at Bombardier, said: "This is good news, however it is as a result of the fact that we are going up a production peak currently, meaning that these positions are only temporary.
"In approximately 12 months' time, we have a sharp drop in production and so we are actively seeking additional work for our Derby facility."
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