Demolition teams have started work on dilapidated streets in Goole as part of a regeneration plan.
More than 100 terraced houses on Richard Cooper Street and Phoenix Street are to be pulled down and replaced with new accommodation.
Some residents had campaigned against the plan and East Riding of Yorkshire Council secured compulsory purchase orders for two properties.
The authority said the project would reduce crime and vandalism in the area.
Mix of homes
Council leader Steve Parnaby said: "I am delighted to see this long-awaited work start on the site.
"This is an exciting project which will make a huge difference to people living in the area and I know that many people living nearby have been waiting for demolition to start and are keen to see this work move forward."
The council said future proposals for the site were being developed with Peter Ward Homes which would see a mix of homes and open space for residents.
The redevelopment is part of the Advance Goole programme, which aims to improve the quality of life for local people.