A 14-year-old boy was seriously hurt when the motorbike he was riding and a car collided in Stockport.
A 20-year-old man who was riding pillion was also hurt when the bike and silver Toyota Avensis crashed on Brinnington Road in Brinnington.
Both were taken to Stepping Hill Hospital with serious head and leg injuries. The car driver was unhurt.
Police are appealing for witnesses to the crash, which happened just after 0920 BST on Thursday, to contact them.