A Nottinghamshire hospital has said it has cut rates of two main infections by half.
King's Mill Hospital in Sutton-in-Ashfield said that cases of MRSA had gone from 31 in 2008/9 to 14 the year after.
Over the same period, cases of clostridium difficile (C. diff) fell from 144 to 63.
Managers said they had looked at all aspects of cleanliness to bring rates down.
The Sherwood Forest Hospitals NHS Foundation Trust said it was aiming to build on the success by installing non-touch hand cleaning stations around the hospital.
Elaine Overton, senior nurse for infection prevention and control at the trust, said: "These hand sanitizer stations will help us tackle infections head on.
"We are committed to providing a hygienic, safe and healthy environment, so we can continue to provide the best care possible for our patients."