A pharmaceutical firm has announced plans to shut its Nottingham site as part of cost-cutting measures.
Vectura says the closure of its Ruddington laboratories, which employ about 100 people, will help save about £6m in the next financial year.
The firm has begun a consultation period with staff, but would not confirm how many jobs are at risk.
Vectura is based in Chippenham, Wiltshire, and also has a site in Cambridge.
It manufactures inhaled medicines for the treatment of respiratory diseases.
Dr Chris Blackwell, the company's chief executive, said a more "cautious environment" meant the firm had to reduce its cost base and focus on nearer-term projects.