Young Knives, Little Fish and Adam Barnes are set to play Truck Store in Oxford to celebrate Record Store Day.
The event is part of an international campaign aimed at encouraging people to support their local record shops.
This year Gorillaz, The Beach Boys and Radiohead are putting out exclusive releases only available in the shops.
Adam Barnes said: "It's great to be involved with something that's supporting our only independent record store in Oxford.
"I'm really excited to have been asked to play and to be the first act on, opening up two days of unbelievable artists."
Truck Store was opened on the Cowley Road in February by Rapture Entertainment in Witney and the organisers behind Truck Festival.
The full stage times are as follows:
Saturday 16 April
2100 Young Knives
1930 Spring Offensive
1830 Half Rabbits
1730 Phantom Theory
1600 Nathaniel Rateliff
1500 Sophie Barker
1400 Adam Barnes
Sunday 17 April
2000 Little Fish
1900 Special guests
1730 Richard Walters
1630 Cat Matador
1530 Message to bears
1430 Good things happen in bad towns
Exclusive records from participating artists will be available when Truck Store opens at 0900 BST Saturday 16 April.