A teenager died and a 45-year-old woman was left fighting for her life after their car was in collision with a lorry in Barnsley.
The crash happened on Moor Lane, Brierley, at 0810 GMT on Wednesday.
The Renault Clio, driven by a 45-year-old woman from Barnsley, crossed the carriageway into the path of an oncoming lorry, police said.
Both occupants of the car were trapped and the front seat passenger, and 18-year-old woman from Barnsley, died.
The car driver, also from Barnsley, was airlifted to Leeds General Infirmary with "life-threatening injuries".
The driver of the lorry, a 63-year-old man from Bradford, was not hurt.