Work has begun to refurbish a former teaching institute which has been listed as one of the most at-risk Victorian buildings in England.
The derelict Wedgwood Institute, in Burslem, is being restored at a cost of more than £850,000, using grant money.
The work is being carried out by Stoke-on-Trent City Council and the Prince's Regeneration Trust (PRT), who will offer it to start-up businesses.
The local authority said it could create about 150 jobs.
Rosie Fraser, from the Prince's Regeneration Trust, said: "It will be a hub for business start-ups and we hope people will come in and there will be ideas flourishing and people will be wanting to come and use these spaces."
The initial building work to carry out urgent roof and weatherproofing repairs and make the ground floor accessible, is expected to be completed in July.
Sarah Lewis, from English Heritage, said: "The Wedgwood Institute is one of the top 6% of listed buildings in the country for not only its architectural splendour but also the social history it embodies."