Six people are to appear in court later charged with drugs and money laundering offences.
The five men and a woman have been charged with conspiracy to supply class A and B drugs as well as money laundering.
The arrests followed a number of searches in the Lisburn area on Tuesday by the PSNI's Organised Crime Branch.
Three other men were released without charge and a fourth man released pending a report to the PPS.
The six people who have been charged are to appear at Lisburn Magistrates Court.