A 26-year-old man is to appear at Downpatrick Magistrates' Court charged with the murder of Paul Owens, 18, who died after being stabbed in Newcastle.
Mr Owens was assaulted on the Bryansford Road near the entrance to Donard Park at about 0100 GMT on Saturday. He died later in hospital.
A 20-year-old woman has been charged with assisting offenders. Both accused will appear in court on Monday.
A 29-year-old man who was also arrested was released without charge.