A famine has been declared in parts of South Sudan, the first to be announced in any part of the world in six years.
The government and the United Nations report that some 100,000 people are facing starvation, with a million more on the brink of famine.
A combination of civil war and an economic collapse have been blamed.
There have been warnings of famine in Yemen, Somalia and north-eastern Nigeria, but South Sudan is the first to declare one.
The famine is currently affecting parts of the Unity state in South Sudan, but humanitarian groups have warned that the crisis could spread if urgent help is not received.
Aid agencies, including the UN World Food Programme (WFP) and the children's fund Unicef, said that 4.9 million people - more than 40% of South Sudan's population - are in urgent need of food.
When is a famine declared?
Food shortages can lead to large numbers of people lacking nutrition, but only rarely do they amount to famine, according to UN humanitarian criteria.
Long periods of drought and other problems reducing the supply of food do not necessarily result in a famine.
A famine is declared only when certain measures of mortality, malnutrition and hunger are met. They are:
- at least 20% of households in an area face extreme food shortages with a limited ability to cope
- acute malnutrition rates exceed 30%
- the death rate exceeds two persons per day per 10,000 persons
The declaration of a famine carries no binding obligations on the UN or member states, but serves to focus global attention on the problem.
The report on Monday said that an increase in humanitarian assistance was needed in order to prevent the famine from spreading to other vulnerable areas.
"If sustained and adequate assistance is delivered urgently, the hunger situation can be improved in the coming months and further suffering mitigated," the report said.
Head of the WFP in South Sudan, Joyce Luma, said that the famine was "man-made" after three years of conflict across the country stifled crop production and hit farmers and rural livelihoods.
The impact of the conflict, combined with high food prices, economic disruption and low agricultural production has resulted in the area becoming "food insecure", the report added.
South Sudan also experienced a famine in 1998, during the war for independence from Sudan.
Last week, the WFP warned that more than 20 million people may face starvation in a series of famines over the next six months.
The WFP's chief economist, Arif Husain, said a combination of wars and drought meant that for the first time in recent years, aid workers were now talking about four simultaneous famines in separate parts of the world.
He added that despite record levels of international humanitarian aid distribution, there was not enough to look after all the people in need.