A military plane with 38 people on board has disappeared en route to Antarctica, Chile's air force says.
The C-130 Hercules transport aircraft took off from Punta Arenas at 16:55 local time (19:55 GMT), and operators lost contact at 18:13 (21:13).
Those missing include 17 crew and 21 passengers.
They were travelling to provide logistical support to a military base on Antarctica's King George Island. A search-and-rescue mission is under way.
What do we know of the disappearance?
Air Force Gen Eduardo Mosqueira told local media that the plane did not activate any distress signal. He said the plane, whose pilot had extensive experience, might have been forced to touch down on water.
An air force statement said that the plane was about 450 miles (725km) into its 770-mile journey when contact was lost, placing it within the Drake Passage. The air force published a map of the plane's last known location on Twitter:
The Drake Passage is a body of water connecting the South Atlantic and South Pacific oceans, and is known for treacherous weather conditions. But Chile's air force said local weather was good at the time of the plane's disappearance.
It also said that the plane would have had enough fuel to keep airborne until 00:40.
Who was on board?
Three of the passengers were Chilean soldiers; two were civilians employed by engineering and construction firm Inproser, who were going to carry out work on the military base; one was a student at Magellanes University; and the remaining 15 passengers were members of the air force, an official said.
The C-130 is also staffed by 17 crew members. The Air Force has published a list of all those on board.
What of the rescue effort?
Air Force Gen Francisco Torres said that the search for the plane had "begun immediately" after it had failed to arrive at the military base in Antarctica.
Four ships and 10 planes from Chile are taking part in the search operation.
Uruguay and Argentina have also each sent a plane to help locate the missing C-130.
An initial overflight of the area where communication was lost failed to yield any sign of the missing plane. Rescuers are currently searching inside a 60-mile radius from the last point of contact.
What has been the reaction?
President Sebastián Piñera said in a tweet that he was "dismayed by the loss".
He cancelled his planned trip to Argentina to attend the swearing-in of President-elect Alberto Fernández and instead went to Cerrillos Air Base in the capital, Santiago, to monitor the search, along with Interior Minister Gonzalo Blumel.
Chile's Defence Minister Alberto Espina has travelled to Punta Arenas.
Chile claims more than 1.2m sq km (463,000 sq miles) of Antarctic territory and operates nine bases there.