At least 68 prisoners have been killed in new fighting at an Ecuadorean prison where more than a hundred inmates died in clashes between rival gangs in September, officials say.
The riot at the Litoral Penitentiary in the city of Guayaquil reportedly began on Friday evening.
Police tactical units who entered the prison buildings found guns, explosives and blades, reports say.
Officials say they have re-gained control of the jail.
Nearly 300 inmates have died so far this year in the country's prisons, and September's gang-related violence was the worst in Ecuador's history.
Some 119 inmates lost their lives during a riot in the Litoral Penitentiary on 28 September.
The latest fighting at the prison in Guayaquil, Guayas province, has also left 25 people injured and follows a smaller armed clash earlier this month in which three inmates were shot dead.
There were reports of further violence at the prison later on Saturday and soldiers were deployed as reinforcements, securing the outside of the facility in armoured vehicles.
Family and friends of prisoners desperate for information gathered outside the building, where a list of victims' names was taped to a post.
"They are human beings, help them," read a banner held by one of the families.
Authorities said the violence started as a territorial dispute between rival groups after a gang leader was released early.
"As this section of the prison was without a ringleader, other gangs tried to... enter to carry out a total massacre," the governor of Guayas province, Pablo Arosemena, told reporters.
He said there were about 700 prisoners in the area of the facility where the deadly riot was taking place.
In a short statement posted to Twitter, President Guillermo Lasso offered his condolences "to the families who have lost loved ones" and said new measures were needed to "fight the mafias that profit from chaos".
On 28 September, inmates from one wing of the prison crawled through a hole to gain access to a different wing, where they attacked rival gang members. Hundreds of officers and army soldiers were deployed to regain control of the complex.
The deadly fight, which saw some inmates decapitated, drew attention to the growing influence in Ecuador of transnational crime gangs such as the Mexico-based Sinaloa and Jalisco New Generation cartels.
Earlier this month in a BBC interview, Mr Lasso insisted that his government was regaining control not only of the prisons but also of areas of Ecuador where drug traffickers had gained a foothold.
He accused previous governments of being "passive" about drug trafficking but warned that rising drug use in the country would take "more than a decade" to tackle.
And he said Ecuador would need international support from neighbouring Colombia, the US and the EU to strengthen its armed forces and police to combat the growing influence of crime gangs.
Ecuador's prisons are currently accommodating about 9,000 more prisoners than they were designed to hold, officials say. The Litoral Penitentiary was designed for 5,300 inmates but currently holds 8,500.