Comedian Samantha Bee has apologised after insulting Ivanka Trump with an obscene phrase on her television show.
Bee was lambasting the White House adviser and US first daughter over the immigration policy of her father President Donald Trump.
Conservatives demanded Bee be fired like Roseanne Barr, whose sitcom was cancelled this week after she posted a racist tweet.
Bee acknowledged on Thursday she had "crossed a line" with her language.
What did Bee say?
On her political commentary show Full Frontal, Bee attacked the president's daughter over a long-standing US policy of separating undocumented immigrant children from their families.
Presenting Obama-era photos of such young people sleeping in cages, Bee said: "Tearing children away from their parents is so evil, it's the inciting incident in almost every movie we've ever cared about."
She said Ms Trump had been "oblivious" recently to post an Instagram photo of herself hugging her child.
"You know, Ivanka, that's a beautiful photo of you and your child, but let me just say, one mother to another, do something about your dad's immigration practices," Bee said.
She then called Ms Trump a "feckless [expletive]", employing an offensive term for part of the female anatomy.
Bee urged the first daughter to confront her father about the policy.
"He listens to you," she said. "Put on something tight and low-cut and tell your father to [expletive] stop it. Tell him it was an Obama thing and see how it goes, OK?"
I would like to sincerely apologize to Ivanka Trump and to my viewers for using an expletive on my show to describe her last night. It was inappropriate and inexcusable. I crossed a line, and I deeply regret it.— Samantha Bee (@iamsambee) May 31, 2018
The immigration issue has risen to the fore recently since it was reported that US authorities had been unable to contact almost 1,500 unaccompanied children placed in the care of sponsors.
The Trump administration has also been criticised for its policy of separating children from parents who cross the US-Mexico border illegally.
The hashtag #Wherearethechildren has been used hundreds of thousands of times on Twitter.
What's the fallout?
White House press secretary Sarah Sanders called Bee's language "vile and vicious".
"Her disgusting comments and show are not fit for broadcast," she added, demanding the cable network apologise.
TBS, which airs Full Frontal, duly obliged by agreeing that Bee's language was "vile and inappropriate".
"Those words should not have been aired. It was our mistake too, and we regret it," said the network's statement.
Shortly beforehand, car retail website Autotrader.com announced it was pulling its ads from the show.
Thank you to those who reached out regarding our sponsorship of Full Frontal. The comments expressed by Samantha Bee were offensive and unacceptable and do not reflect the views of our company. As a result, we have suspended our sponsorship of Full Frontal with Samantha Bee.— Autotrader (@AutoTrader_com) May 31, 2018
Bee's outburst comes amid a public debate over incendiary language by TV personalities.
ABC cancelled the sitcom Roseanne this week after its star likened an African-American former aide to President Barack Obama to an ape.
The chief executive of Disney, which owns ABC, said sorry to the ex-adviser, Valerie Jarrett.
That has led President Trump to demand an apology for all the "horrible" things said about him by the entertainment conglomerate's TV personalities.
Iger, where is my call of apology? You and ABC have offended millions of people, and they demand a response. How is Brian Ross doing? He tanked the market with an ABC lie, yet no apology. Double Standard!— Donald J. Trump (@realDonaldTrump) May 31, 2018
First Lady Melania Trump has said "the double standard is truly astounding", conservative news organisation the Daily Caller reported.
Barr also weighed in on the situation on Twitter.
please don't compare me2 other people who have said horrible things. I only care about apologizing 4 the hurt I have unwittingly & stupidly caused. I humbly confess contrition & remorse. I failed2 correctly express myself, & caused pain2 ppl.— Roseanne Barr (@therealroseanne) May 31, 2018