Isle of Man Commonwealth Youth Games team manager Trevor Taubman says his team are "fit and raring to go" when the island hosts the 2011 event.
The host nation has selected a team of 33, with representation in each of the seven sports.
The Earl of Wessex will open the Games at Thursday's opening ceremony.
"They've all completed their final training sessions and are really looking forward to their competitions getting under way," said Taubman.
"We know the standard is going to be very high but we are very confident that we can win medals in several sports.".
The Isle of Man will compete in swimming, athletics, badminton, boxing, cycling, gymnastics and rugby sevens.
Swimmer Grant Halsall has been selected as the team captain and will be a strong medal hope in the 50m, 100m and 200m backstroke events, whilst discus thrower Andrea DeBruin will be the island's first medal hope on Saturday morning.
More than 1,000 competitors, from 67 Commonwealth nations, will compete in the seven-day sporting festival.
ISLE OF MAN COMMONWEALTH YOUTH GAMES TEAM
Athletics: Reagan Dea (high jump), Andrea DeBruin (discus).
Badminton: Ben Li, Cameron Avery, Mathew Nicholson, Kayleigh Callow, Laura Beggs.
Boxing: Eddie Rennie (64kg light-welterwight).
Cycling: Alex Haddock, Jonathan Cregeen, Thomas Mazzone, Warwick Sanderson.
Gymnastics: Anand Patel, Brandon Garret, Emily Dale-Beeton, Kaitlin Kneen, Rebecca Johnson.
Rugby: Andrew Evans, Ben Kelly, Daniel Bonwick, James Olerenshaw, Jordan Hogan, Mark Oldfield, Nathan Pierce, Phil Cringle, Liam Murphy (captain), Conor Stephens, Duncan MacGregor, Alex Sharpe.
Swimming: Grant Halsall (team captain), Tom Bielich, Laura Kinley, Charlotte Atkinson.