Jason Smyth was well outside his personal best as he finished fifth and last in the 100m B race at Saturday's Diamond League meeting in New York.
Smyth clocked 10.60 which left him .10secs behind Jamaican winner Kimmari Roach in a race run in wet conditions.
The wind reading was -1.5 but the gusty conditions affected the sprinters and athletes in several other events.
Smyth's time looked even more respectable when Steve Mullings pipped Tyson Gay to win the A race in 10.26.
Mullings' time was almost half a second slower than he produced in Eugene last weekend.
Derryman Smyth will run next week at the European Team Championship in Turkey.
Roach won the B event in 10.50 ahead of Trinidadian duo Rondel Sorrillo (10.53) and Marc Burns (10.56) plus American Leroy Dixon.
Smyth's time was .38secs outside his Northern Ireland record set last month in Florida.
Burns has a personal best of 9.96 while Sorrillo's lifetime best is 10.18 with Roach having a 10.13 clocking to his name.
Smyth was hoping that racing against world-class opposition would help spur him to achieve the World Championship and Olympic Games standard of 10.18.
The Londonderry man's ambition is to compete at both the Olympic Games and Paralympics in London next year.
David Gillick also appeared to struggle in the windy conditions in New York as he finished fourth in the B 400m race in 46.64.
Britain's Michael Bingham was the only finisher under 46 seconds as he won in 45.42.
Erison Hurtault of the Dominican Republic took second in 46.30 ahead of American Jamaal Torrance (46.61) and Gillick.
The Irishman - whose Irish record is world-class 44.77 - clocked a mediocre 46.80 seconds on his season opener in Florida last weekend.
Fionnuala Britton and Stephanie Reilly both produced tremendous performances as they set new personal bests and World Championship and Olympic Games standards in the 3000m steeplechase.
Britton clocked 9:37.60 - cutting almost four seconds off her previous best - which left her in fifth while Reilly was .09secs inside the Daegu and London standards as she finished in 9:42.91.
Reilly set her previous best of 9:48.94 at last year's European Championships in Barcelona.
Alistair Cragg also showed a return to form as he achieved the Daegu and London standards with a 13:12.23 clocking as he finished eighth in a high-class 5000m.
It was Cragg's best performance for several years as he finished seven seconds behind winner Dejen Gebremeskel (13:05.22) who held off Kenyan-born American Bernard Lagat.
Cragg set his personal best of 13:07.10 in 2007.