The British record holder used his greater strength to pull away from American Brian Ollinger and win in eight minutes 37 seconds in Gateshead.
Farah, who also in Daegu, told BBC Sport: "I wanted to come back home and win.
"It's nice to see so many people come and show their support."
"I've got a couple of weeks off now before starting the new season slowly," Farah added.
Looking ahead to the 2012 Olympics, Farah said: "You've got to forget about this year and focus on next, I've got to stay injury free and keep doing what I am doing."
Farah was part of the Great Britain and Northern Ireland team who took on one of the strongest athletics countries in the world, the United States, at Gateshead's Quayside.
Hannah England, and came fifth in Brussels on Friday, beat fellow Brit Helen Clitheroe in the women's mile event. Jenny Meadows came in fourth.
In the men's mile, former world champion Bernard Lagat eased to victory in just four minutes and six seconds, ahead of teammate Kyle Miller. UK and NI champion Andrew Osagie grabbed third spot.
Former Olympic champion Dawn Harper got her own back on US compatriot Danielle Carruthers for snatching the World Championship bronze medal from her grasp by coming first in the women's 100m hurdles.
Jeremy Hicks of the US won the men's long jump with a leap of 7.84m while four-time world champion Dwight Phillips, who said prior to competing that the run-up was too short, finished fourth.
Becky Holiday claimed another victory for the US in the women's pole vault, her clearance of 4.27m easily beating Britain's Holly Bleasdale, who only cleared 4.12m.
Harry Aikines-Aryeetey outsprinted team-mate Christian Malcolm to win the men's 100m in 10.28 seconds, while US world 100m champion Carmelita Jeter turned up the gears to come in ahead of Briton Anyika Onuora in the 150m.
Amercian Walter Dix, in Brussels on Friday, won the men's 150m, finishing ahead of Briton Marlon Devonish.
Dix said: "I think I found some flaws in my race against Blake and it has made me more motivated for 2012."
In the final race of the day, four of the top five from Daegu lined up in the men's 110m hurdles, with newly-crowned world champion Jason Richardson smashing the competition record to triumph in 13.16 seconds from fellow American David Oliver.
Andy Turner eased up after the final hurdle, allowing British team-mate William Sharman to come through for third in 13.82 seconds.
The result secured a 7-3 overall victory for the United States.