Former world champion Tyson Gay has targeted breaking his personal best this year, ahead of Thursday's Diamond League event in Lausanne, Switzerland.
The 30-year-old American is the star attraction in the 100m and is hoping to break his career-best 9.69 seconds, set in 2009, as he prepares for August's World Championships in Moscow.
"I haven't set a PB for four years. I'm hoping to do that this year," he said.
Britain's Christine Ohuruogu will run in the women's 400m in Lausanne.
The London 2012 silver medallist, 29, will face Botswana's Amantle Montsho again after beating the 30-year-old world champion in Birmingham's Diamond League event on Sunday.
Gay will face former Commonwealth Games champion Asafa Powell, 30, and 37-year-old former world champion Kim Collins in Switzerland, but Usain Bolt will not feature in the showpiece race.
Olympic champion Bolt, 26, will run in the 200m in Paris on Saturday instead but Gay is looking forward to facing the Jamaican over both distances at the World Championships.
"We all know Usain performs well at major championships. I'm just hoping I'm at my best and I give it my all, whatever the outcome may be," Gay said.
"It's been a long time since I doubled at a major championships, so it's good to be able to do that again."
Australia's London 2012 gold medallist Sally Pearson will be looking for revenge over Dawn Harper-Nelson in Lausanne after the American beat her in Sunday's 100m hurdles.
British record holder Shara Proctor will feature in the women's long jump, Olympic bronze medallist Robbie Grabarz competes in the men's high-jump and Andrew Osagie runs in the men's 800m.
However, Dai Greene has pulled out of the 400m hurdles after undergoing a blood test for a minor virus.