Laura Muir and Allan Smith will both face opposition from compatriots in Saturday's Glasgow International Match.
Claire Gibson will run against Muir in the 800m after the European Under-23 bronze medallist was chosen for
David Smith had been chosen along with Gibson for the Commonwealth Select.
The two high-jumping Smiths will be up against training partner Robbie Grabarz, who will represent Great Britain and Northern Ireland.
Olympic silver medallist Erik Kynard, representing the United States, completes the high jump line-up for the annual event involving four teams.
Jamie Bowie has been given the chance to build on
The 24-year-old's time of 47.09sec at Saturday's National Open in the same venue was the second-fastest Scottish men's indoor 400m of all time.
Having taken more than half a second off his personal best, Bowie will go into the match full of confidence as he faces eight-time global medallist Chris Brown, the Bahamas sprinter representing the Commonwealth, and Nigel Levine, the semi-finalist at the world championships in Moscow being in GB&NI colours.
Guy Learmonth also returns to the Emirates after the 21-year-old got his season off to a winning start in the 800m at the weekend.
Moscow 1500m finalist Chris O'Hare will be looking to continue from where he left off in 2013, during which he raced to a Scottish indoor record of 3:37.25.
As previously announced, Eilidh Child will captain the home team and she will face fellow world 4x400m bronze medallist Margaret Adeoye, the USA's world and Olympic 4x400m gold medallist, Francena McCorory, and Nigeria's Regina George over two laps.
Scottish Athletics director of coaching Stephen Maguire thinks it will prove to be a great help in preparing his squad for this year's Commonwealth Games in Glasgow.
"It will be a massive experience for the Scotland team," he said.
"It will be a sold-out Emirates Arena and gives the team an opportunity to compete in front of a Scottish crowd and that is great preparation and that's the way I'm looking at it.
"The Scotland team gives the event a different dynamic.
"When you actually sit down and think about it, you look at the likes of Laura Muir, Eilidh Child, Chris O'Hare, they are as good as anything in the US or the British teams."
The Commonwealth team includes Englishman Dwain Chambers in the 60m, former world 100m champion Kim Collins, of St Kitts and Nevis, in the 150m, as well as the Olympic gold medal-winning Bahamas 4x400m team of Demetrius Pinder, Michael Mathieu, Ramon Miller and Brown.
World indoor silver medallist Augustine Choge (Commonwealth), European cross-country bronze medallist Andy Vernon (GB&NI) and world indoor champion Bernard Lagat are the stiff competition for Scotland's Mark Mitchell in the 3000m.
60m: Stephen Dunlop
150m: Ryan Oswald
400m: Jamie Bowie
600m: Guy Learmonth
1500m: Chris O'Hare
3000m: Mark Mitchell
60m hurdles: David Feeney
Long jump: John Carr
High jump: Allan Smith
4x400m: Jamie Bowie, Greg Louden, Anthony Young, Martin Lipton, David Martin
60m: Kathryn Christie
150m: Kathryn Christie
400m: Eilihd Child
800m: Laura Muir
1500m: Josephine Moultrie
60m hurdles: Gemma Werrett
Long jump: Jade Nimmo
Pole vault: Henrietta Paxton
4x400m: Eilidh Child, Gemma Nicol, Diane Ramsey, Zoey Clark, Laura Muir
T12 60m: Libby Clegg
T 44 long jump: Steph Reid