Split by the river that gives the city its name, the rivalry between Hull KR in the east and west-side Hull FC is as passionate as ever.
If local bragging rights were not enough to ramp up the intensity, the tussle for a place in Super League's top eight has added further spice to Friday's encounter.
FC's win against Castleford last weekend put them in pole position for a place in the elite competition after the split, while Rovers are two points behind with two games to play.
Italy international team-mates Josh Mantellato and Mark Minichello will find themselves on opposite sides of the field in the third derby of the season at Craven Park.
They discuss the battles so far, what it means to play in this most famous of rivalries and the price victory or defeat will have coming into this most crucial period of the Super League campaign.
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Watch all the tries from the weekend's games on the Super League Show.