Belfast heavyweight Martin Rogan is to fight Bedford's Matt Skelton in the King's Hall on 12 November.
Former Prizefighter winner Rogan became the first man to stop Skelton in a 2009 fight for the Comonwealth title.
Skelton, 44, is a former British, Commonwealth and European champion and also held the WBU belt.
Rogan had wanted to take on Panama's Lewis Andreas Pineda on 27 October for the lightly-regarded WBU version but the British Board blocked the contest.
The 40-year-old cabbie has not fought since November 2010 when he beat Germany's Werner Kreiskott on points in a six-round Castlebar contest.
"I hope to put on a show and win in Belfast," said Rogan.
"But I am going to have to work very hard because Skelton will try to grind me down.
"I am sure everyone remembers the last time we met. It went down as one of the best British heavyweight fights of the decade."