Nine of Northern Ireland's Commonwealth Games representatives will be in action at the Belfast International meeting at the Mary Peters Track on 2 July.
Ben Reynolds, who ran 13.49 seconds at the event last year to break his own national 110m hurdles record, returns.
Zoe Brown, Amy Foster, Katie Kirk, Christine McMahon, Peter Glass, Jason Harvey, Daniel Mooney and Leon Reid also compete ahead of Glasgow 2014.
Mooney will face Australian record holder Ryan Gregson in the 1500m.
Gregson, a semi-finalist at the 2012 Olympics, clocked three minutes 31.06 seconds in 2010 and has a 3:36.17 to his credit this season.
In-form Irish athlete Paul Robinson, who set a personal best for the mile of 3:54.77 in Oslo recently, will also be in the field.
Robinson, who will use the Belfast race as part of his preparations for the European Championships in August, set a 1500m personal best of 3:35.22 last season.
Athletics Northern Ireland will "relish the opportunity to welcome world-class athletes", said general secretary John Allen.
He added: "Many of the Northern Irish athletes competing will be in the final stages of their training ahead of the Commonwealth Games in Glasgow.
"This will be the last chance for local athletics fans to cheer on their favourite Northern Irish athletes before they depart for Glasgow."
A number of other prominent Irish, British and international athletes are likely to be added to the meet, which starts at 18:30 BST, in the coming days.