Durham head coach Geoff Cook says the England and Wales Cricket Board has made positive improvements to the 2012 Twenty20 fixture schedule.
Last year's T20 matches were intertwined with four-day games but have been isolated for the forthcoming season in new region-based groups.
"It looks a lot more civilised and organised," Cook told BBC Newcastle.
"If we get the chemistry right and get off to a good start it could be a good Twenty20 as well as four-day campaign."
Cook added: "We've got five days preparations and there are no interruptions for four-day cricket."
Meanwhile the County Championship calendar sees the return of Middlesex and Surrey to Division One after five and three-year absences respectively.
In addition those fixtures will take Durham back to the traditional test venues of Lord's and the Oval.
"It's nice to play on grounds of that historical relevance," Cook added.
"For young players like Scott Borthwick or Ben Stokes who've never played there before. It's a wonderful opportunity."