|Derbyshire 124-7 (18.5 ov) beat Lancashire 122-8 (20 ov) by three wickets|
Wes Durston took 2-16 and scored 56 as Derbyshire dented Lancashire's hopes of reaching the FL t20 quarter-finals.
Rana Naved-ul-Hasan (3-20) restricted Lancashire to 122-8 from 20 overs.
Durston, opening the bowling for Derbyshire, removed top scorer Steven Croft for 48, having had Stephen Moore stumped for nought in the first over.
His half-century came from 24 balls and, despite a flurry of wickets late on, Derbyshire made it home by three wickets with seven balls remaining.
It was only their second win of the group stages - the other had come against Lancashire in a rain-affected clash earlier in the tournament.
Gary Keedy (2-20) and Glen Chapple (2-32) caused some late nerves for the visitors, who move off the bottom of their group at Leicestershire's expense.