Australia captain Michael Clarke has been ruled out of October's one-day series against Pakistan in the UAE with a "significant" hamstring injury.
The 33-year-old batsman missed much of the recent tour of Zimbabwe, when George Bailey led the side.
Australia physio Alex Kountouris said: "The scans show tendon damage, which complicates the recovery."
The limited-overs series starts with a Twenty20 in Dubai on 5 October, followed by three ODIs.
|Pakistan v Australia (in the UAE)|
|5: Twenty20 international, Dubai (d/n) (17:00 BST)|
|7: 1st ODI, Sharjah (d/n) (11:00 BST)|
|10: 2nd ODI, Dubai (d/n) (11:00 BST)|
|12: 3rd ODI, Abu Dhabi (d/n) (11:00 BST)|
|15-18: v Pakistan A, Sharjah (07:00 BST)|
|22-26: 1st Test, Dubai (07:00 BST)|
|30-3 Nov: 2nd Test, Abu Dhabi (06:00 BST)|
The sides then meet in two Tests, for which Clarke - a veteran of 105 Tests and 237 one-day internationals - will be assessed nearer the time.
It marks the start of a busy period for Australia, who play South Africa at home in three T20s and five ODIs in November.
They also welcome India for four Tests before staging a triangular one-day tournament involving England and India in January.
They then host the World Cup, with their first game against England in Melbourne on 14 February.