Surrey all-rounder Zafar Ansari has been named in England's Performance Programme (EPP) and Lions squad for the winter's tour programme.
Worcestershire duo Joe Clarke and Ross Whiteley win first Lions call-ups.
Hampshire's James Vince will captain the Lions in a five-match Twenty20 series with Pakistan A in December.
Vince, who was named in England's T20 squad to take on Pakistan in the United Arab Emirates, will lead six other players with international experience - Sam Billings, Chris Jordan, Stephen Parry, Reece Topley, David Willey and Ansari, who, like Vince, played in an abandoned one-day international with Ireland in May.
Ansari's inclusion in both the Lions and EPP squads will be subject to a further medical review.
"It is hugely important that we have a reserve of players who are ready to perform on the international stage when they get the opportunity," said national selector James Whitaker.
"The EPP and the England Lions play a vital role in identifying and developing the next generation of England cricketers.
"With the 2016 ICC World Twenty20 in India just six months away, the five-match T20 series for the Lions against Pakistan A will form a particularly important part of our preparations for the tournament, ensuring that we can draw on a wider group of players who have recent experience of playing T20 cricket in sub-continental conditions."
The Lions will return to Dubai to play a five-match one-day international series against Pakistan A in January.
England Lions Twenty20 squad (v Pakistan A): J Vince (captain) (Hampshire), Z Ansari (Surrey), J Ball (Notts), S Billings (Kent), (wkt), J Clarke (wkt) (Worcs), D Bell-Drummond (Kent), B Foakes (Surrey) (wkt), L Gregory (Somerset), C Jordan (Sussex), D Malan (Middlesex), T Mills (Sussex), S Parry (Lancashire), R Topley (Essex), T Westley (Essex), D Willey (Northants), R Whiteley (Worcs).
England Performance Programme 2015-2016: Z Ansari, D Briggs (Hampshire), J Clarke, D Bell-Drummond, B Foakes, L Gregory, C Jordan, D Malan, S Parry, T Westley, R Whiteley, J Vince, J Ball, C Miles (Glos), T Mills, C Overton (Somerset), J Overton (Somerset), O Stone (Northants).