World champion Mark Cavendish won the second stage of the Tirreno-Adriatico, his fourth victory of the season.
The Team Sky rider beat Oscar Freire of Spain and American Tyler Farrar in the final sprint.
He clocked 6 hours, 32 minutes, 32 seconds over the largely flat 230km leg from San Vincenzo to Indicatore.
Australian Matt Goss, Cavendish's former team-mate at HTC-Highroad, retained the overall lead in the Italian coast-to-coast race.
The third stage on Friday takes the riders 178km from Indicatore to Terni.
Cavendish, in his debut season for Team Sky, and last month.