Britain's Chris Froome finished third on stage five of the Criterium du Dauphine to move fifth overall.
Froome, who won this race before winning the Tour de France in 2013, is 41 seconds behind leader Tejay van Garderen, who was second on Thursday.
French rider Romain Bardet won the 161km mountainous stage.
Britain's Simon Yates finished 50 seconds behind Bardet in fifth, with the Orica rider sixth overall - tow seconds behind Froome.
Thursday's route, from Digne-les-Bains to Pra-Loup, is the same as the peloton will negotiate on stage 17 of the Tour de France on 22 July.
The race, a warm-up to the Tour de France which starts on 4 July, ends on Sunday.
Stage 5 results
1 Romain Bardet (Fra/AG2R) 4hrs 31mins 22secs
2. Tejay van Garderen (US/BMC Racing) +36secs
3. Chris Froome (GB/Team Sky) +40secs
4. Benat Intxausti (Spa/Movistar) +42secs
5. Simon Yates (GB/Orica) +50secs
6. Louis Meintjes (SA/Team MTN)
General Classification after stage 5:
1 Tejay van Garderen (US/BMC Racing) 18hrs 03mins 22secs
2 Benat Intxausti (Spa/Movistar) +17secs
3 Romain Bardet (Fra/AG2R) +20secs
4 Michele Scarponi (Ita/Astana) +31secs
5 Chris Froome (GB/Team Sky) +41secs
6 Adam Yates (GB/Orica) +43secs