Dame Sarah Storey will return to competitive action for the first time since London 2012 when she rides in Newport International Para-cycling Cup.
The 11-time Paralympic gold medallist took a break from the sport following the birth of her daughter Louisa.
The Para-cycling Cup is a three-day event that starts on 29 November.
Storey, 35, said: "I can't wait to race again. I'm looking forward to being able to measure my fitness against the best in the world."
She won four gold medals at London 2012, taking the C4-5 road race, the road time trial, the 500m time trial and the individual pursuit titles.