European, World and Paralympic T44 100m champion Jonnie Peacock will miss Sunday's IPC Grand Prix final in Birmingham because of injury.
The 21-year-old single-leg amputee, who was due to race American rival Richard Browne, has had to withdraw after picking up a sore on his leg.
He joins fellow Britons David Weir (injury) and Libby Clegg (illness) in pulling out of the event.
"I'm gutted to have to withdraw with a small injury," said Peacock.
"After winning European gold this week, I was really looking forward to putting a marker down against the likes of Richard Browne and the rest of the guys lining up in the 100m.
"I've been advised by the medical team to rest. I know I've got to do what's right for my body and it's a big few years ahead for me, which is why I've had to make this difficult decision.
"I'm really sorry to all my fans, but I know it's going to be a great show in front of a full house in one of the best athletics meets in the world."
Among the British stars who will be competing at the event - which follows the Diamond League meeting - are European champions Dan Greaves and Aled Davies (discus), wheelchair racers Hannah Cockroft, Jade Jones and Sammi Kinghorn, and long jumper Stef Reid.