Crewe 2-0 Stockport
Stockport were relegated from the Football League after an own goal from Alan Goodall and a Clayton Donaldson strike earned Crewe all three points.
The Hatters, who were all but down before this match, fell behind when Lee Bell's free-kick was headed past his own goalkeeper by Goodall.
Donaldson made the points safe shortly afterwards with a neat low finish.
Anthony Elding came close to a consolation for the visitors who go into non-league for the first time.
Crewe manager Dario Gradi told BBC Radio Stoke:
"It wasn't one to remember, but it's not easy. It was windy and the ball was bouncing around.
"We ended up with three more of our kids on and that will be good for them.
"Ollie Turton didn't do anything wrong and Casper Hughes did what he can do, so that's a bonus for us."
Stockport County caretaker manager Ray Mathias told BBC Radio Manchester:
"If you miss chances away from home, you are going to get punished sometime or other and it happened.
"I thought we bettered them by a mile and they had to change their system to stop us playing.
"I've been to some places and had some fans but they've been electric all afternoon; they were magnificent."