Blackpool boss Ian Holloway insists his side's chances of a win over Manchester United on Sunday do not depend on the champions fielding a weakened team.
Holloway said the theory is "baloney", but also alleged that the Premier League would be glad to see the Seasiders drop out of the division.
"They will be relieved if we lose and get relegated. Then I am not badgering them," said Holloway.
The Premier League rejected the claims, insisting it had "no preference".
"We don't wish any team to be relegated," a Premier League spokesman told BBC Sport.
"At the end of the season the league table is the league table and those who deserve to get relegated, get relegated.
"We have no preference over which team goes down."
Holloway vociferously defended his corner against a Premier League charge earlier in the season after coming in for criticism for making 10 changes in his selection for the 3-2 defeat against Aston Villa.
The Premier League fined Blackpool £25,000 for fielding a weakened team, while Wolves were handed a similar punishment for an offence in the previous season.
Manchester United boss Sir Alex Ferguson has already won the Premier League title and have the Champions League match against Barcelona on 28 May to consider when it comes to picking his side to face Blackpool.
Holloway believes his United counterpart may also be offended by suggestions that he would not want to win his side's final home game of the season.
"I am so annoyed. Sir Alex Ferguson is a winner. He would never dream of not being interested in winning any match," said the 48-year-old, whose side led 2-0 before losing 3-2 in January's reverse fixture.
"That man deserves to pick whatever team he wants to pick. No one should question it.
"Those people running the game, what planet are they on? They must have beamed down from planet Zarf.
"How dare they talk about Sir Alex like that? Haven't they seen how successful he is?"
Ferguson made eight changes for the second leg of his side's Champions League semi-final against Schalke, but United went on to win 4-1 on the night to underline the strength in depth at Old Trafford.
"Ask Schalke if they think Manchester United have a weak team," added Holloway.
"On Sunday, we have to try and do the impossible. It's got to be perfect. No one else has beaten them. And if we do, they might get fined because we are rubbish."
Blackpool are one of five clubs - along with Blackburn, Wolves, Birmingham and Wigan - who could join West Ham in the Championship next season.
With just one point covering the five relegation candidates, Holloway side's fate is partly dependent on other results.
Eighteenth-placed Blackpool, could be relegated despite becoming the first side this season to win at Old Trafford, or lose and stay up.