African champions Burkina Faso began their U17 World Cup campaign in disappointing fashion as they lost their opening Group E game to Panama.
The Central Americans won on their U17 Cup debut thanks to Jorman Aguilar's 22nd-minute goal in Queretaro.
Elsewhere, Ivory Coast also suffered defeat in their maiden Group F clash.
Despite taking the lead against Australia, they went down 2-1 in Gaudalajara.
Souleymane Coulibaly opened the scoring after 18 minutes to give the Baby Elephants a half-time lead.
But second-half goals from Jesse Makarounas and Dylan Tombides, striking thirteen minutes from time, sealed Australia's win.
Brazil top Group F on goal difference above Australia after the South Americans thumped Denmark 3-0.
Meanwhile, Germany are the comfortable leaders in Burkina Faso's group.
The European side destroyed Ecuador's youngsters with a 6-1 victory in Queretaro and Burkina Faso will be wary of meeting Germany in their next fixture on Thursday.
Ivory Coast take on Denmark in Guadalajara, also on Thursday.
The defeat mean that only one African side - Congo - won a match after the first round of matches at the tournament, with Rwanda also going down this week.