Berwick triumphed on penalties against Ramsdens Cup opponents Clyde after the two sides were drawn after extra time.
The visitors were two up early on, Lee Currie and Damon Gray firing home.
Clyde's Patrick Scullion had a penalty saved before Daniel Fitzpatrick's strike and Stephen McDonald's header levelled the game.
After a goalless extra time, Scullion missed from the spot again and Craig Tully also missed from 12 yards, meaning Berwick won the shoot-out 4-3.
Clyde: Mental, Brown, Sharp, Hay, Tully, Neill, Sweeney, Patrick Scullion, Fitzpatrick (Irvine 72), McDonald (Oliver 96), Cusack (Gray 106). Subs Not Used: Hutchison, Ramsay.
Booked: Sweeney, Brown.
Goals: Fitzpatrick 36, McDonald 51.
Berwick: Barclay, Walker (Elliot Smith 106), Thompson, McLean, McLeod, McLaren, Lee Currie, Paul Currie, McDonald, Noble (Darren Smith 60), Gray. Subs Not Used: Gall, Deland, Little.
Booked: McLaren, McDonald, Lee Currie.
Goals: Lee Currie 4, Gray 10. Berwick win 4-3 on penalties
Ref: Stevie O'Reilly