Goalkeeper Lee Butcher saved two penalties as 10-man Leyton Orient beat Southend 4-3 in a shoot-out to reach the second round of the Carling Cup.
Butcher kept out spot-kicks from Liam Dickinson and JP Kalala before Jamie Cureton converted the winning penalty.
Michael Richardson had headed the O's in front from 12 yards but Mark Phillips nodded in to level.
Orient then had Jonathan Tehoue sent off for headbutting Luke Prosser but Butcher's heroics helped them through.
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Southend manager Paul Sturrock told BBC Essex:
"We've very disappointed, with having an hour of being able to play against 10 men.
"(We had) several chances, I thought their goalie had an excellent performance.
"We put a reasonable performance in, it was just our final finish that let us down."