Cameroon and Marseille midfielder Stephane Mbia has been ruled of action for at least six weeks after fracturing a bone in his left foot.
The injury means he will miss the Indomitable Lions' crucial 2012 Africa Cup of Nations qualifier at home to Mauritius on the first weekend in September.
Mbia sustained the injury late in Marseille's 2-2 draw with Auxerre on Sunday, when an opposing player fell on him.
Marseille say the 25-year-old will not "return to competition for at least six weeks."
Cameroon are struggling in third place in Group E of the Nations Cup qualifying - five points behind leaders Senegal with two matches remaining.
Only the top team in the group is guaranteed a place at the finals in Equatorial Guinea and Gabon next year.
There are also two places for the best runners-up from the 11 groups.
The Indomitable Lions' final qualifier is in October against second-placed DR Congo.