Matt Nemes saved a last minute penalty to earn Southport a thrilling win over AFC Telford, who almost came from 3-0 down to grab a point.
The home side raced clear thanks to Shaun Whalley's well-placed shot, Dan Walker's low drive and Kevin Lee's header from Andy Owens' centre.
But Telford battled back through a Gregg Mills free kick and Andy Brown's close range finish.
Nemes saved Sean Newton's weak penalty to win it for a relieved Southport.
Southport: Nemes, Lee, Akrigg, Davis, Owens (Lever 77), Brown (Benjamin 90), Moogan, Poku, Whalley, Gray (Osborne 75), Walker.Subs Not Used: McMillan,Ordish.
Booked: Akrigg, Moogan, Poku, Lee.
Goals: Whalley 14, Walker 17, Lee 20.
AFC Telford: Young, Salmon (Meechan 75), Whitehead, Preston, Newton, Davies (Rooney 65), Valentine (Samuels 46), Trainer, Mills, Brown, Sharp. Subs Not Used: Robinson, Killock.
Goals: Mills 33, Brown 35.
Ref: Scott Duncan (Tyne & Wear).