Ipswich manager Paul Jewell's misery continued as in-form Blackpool condemned his strugglers to a fourth Championship defeat of the season.
Gary Taylor-Fletcher tapped in Billy Clarke's cross in the 49th minute to claim his second goal of the season.
And midfielder Barry Ferguson, a summer signing from Birmingham, opened his account for the Tangerines with a fine finish from 12 yards on the hour mark.
Ipswich's only real chances came from a number of long-range efforts.
The visitors did go close early on when former Cardiff striker Michael Chopra fired goalwards from 12 yards, but his effort was blocked by Ian Evatt six minutes in.
Moments later, Town's veteran midfielder Jimmy Bullard hit a shot which flew narrowly wide from 30 yards before team-mate Carlos Edwards hit a fierce 35-yard effort which went over the crossbar.
Blackpool gradually steadied themselves when striker Brett Ormerod hit an 18-yard shot which sailed just wide in the 16th minute, after which chances were relatively scarce before the break.
The hosts broke the deadlock quickly in the second half when Clarke was afforded time and space down the left flank before delivering a cross for Taylor-Fletcher, who arrived late to convert with his right foot from six yards out.
Former Rangers man Ferguson saw a 35-yard effort sail over the crossbar, but he scored after latching onto Ormerod's fine pass to crash home an effective shot.
Ipswich striker Daryl Murphy missed two half-chances as they failed to trouble the home defence in the closing stages.