Kettering Town boss Morell Maison and coach Nicky Eaden have left their roles at the Blue Square Bet Premier club.
The pair took charge in June, but have seen the Poppies pick up just five points from their seven league matches.
A statement from Maison on the Poppies website read: "Although we have had to cope with several injuries, I understand that results at this time are of paramount importance.
"It is in all parties' interests for me to step aside from the football."
He added: "I am confident that performances will improve but I do not want to risk supporter frustrations with performances detracting from the vital project the club has started at Nene Park.
"I am convinced that the first team squad that has been put together is a very strong one that will, when key players return, prosper under whichever manager the chairman sees fit to bring in."
Maison states that he will remain with the club, focusing on "other areas which will assist securing the long term sustainability of the football club".
He added: "The confirmation of our move to Nene Park increased the level of expectation on the field but also presented the club with several non-footballing challenges.
"In addition to my management position, I have spent considerable time working with the club off the field.
"Although it was felt both roles could be balanced, the team has struggled in its opening games and ultimately this responsibility falls on my shoulders."
The announcement of Eaden's departure came less than two hours before Maison's statement.
The former Barnsley and Wigan full-back had been a player-coach with the Poppies, and helped them to Blue Square Bet North success in 2007/08.
He was brought back to the club in June to assist Maison.