Norwich City boss Paul Lambert has said he has no qualms with making changes to his side in order to get results.
"Any decision you make, whether it's Grant or whoever, it's really, really tough," Lambert told BBC Radio Norfolk.
"But that's my job, to try and pick a winning team to make this club as successful as it can be."
Holt, last season's top scorer, had started every Premier League game this campaign until the trip to the Reebok Stadium.
"To be fair to Grant he was excellent about it, he understood the reasons why I did it," Lambert explained.
"I spoke to him on Thursday about why I was doing it, he was great about it."
Another man to make way was central defender Ritchie de Laet, on loan from Manchester United.
The 22-year-old, who had also featured in every league game so far, was replaced by Russell Martin, a player more recognised as a right-back.
"It was a decision I decided to make to take Ritchie out of the firing line," said Lambert.
"Some of the goals have probably been hurting Ritchie a little bit, his general performances have been excellent.
"He's had bad luck with individual errors, I thought he's only a young lad, take him out of the firing line and put Russell in."